the Research of Analgesia and Sedation Effect of Remifentanil on ICU Short Operation

• Status: Unknown status
• Trial end date: 2016-09-01
• Target enrollment: 0
• Participant gender: All

Summary

Remifentanil is one kind of opiates with strong analgesic effect,which has the rapid onset and short lasting duration. Remifentanil usually is used to help reducing the pain of patients with mechanical ventilation in ICU. Maybe it can also be used to ease the pain in ICU small short time operation.The purpose of this study is to determine (1) whether remifentanil is effective in small short time operations in ICU or not, (2) the save range of remifentanil in small short time operations in ICU, (3) and the adverse reaction that happens in these operations.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: The First Affiliated Hospital of Zhengzhou University
• Collaborator: Yichang Humanwell Pharmaceutical Co.,Ltd
• Treatments: Anesthetics; Lidocaine; Midazolam; Remifentanil

Criteria

Inclusion Criteria:

• critically ill patients need endotracheal intubation

• tracheotomy

• central venous puncture

• pleural puncture

• abdominal puncture

• lumbar puncture

• bone marrow puncture

• fiber bronchoscopic examination

• other small short-time operations

Exclusion Criteria:

• patients allergic to opioids

• in pregnancy or in feeding

• with myasthenia gravis

• with hypovolemia,

• take monoamine oxidase inhibitor(MAOI) in 14days

• in coma and GCS<8

• with bradycardia or hypotension