the Remineralizing Self-Assembling Peptide P11-4, 2% Arginine Enriched Sodium Fluoride and Functionalized Tri Calcium Phosphate Fluoride White Spot Lesions

• Status: Not yet recruiting
• Trial end date: 2024-01-01
• Target enrollment: 0
• Participant gender: All

Summary

The aim of the current study is to compare the remineralizing ability of Self-assembling peptide P11-4, 2% Arginine Enriched Sodium Fluoride and Functionalized Tri Calcium Phosphate Fluoride varnishes in treatment of white spot lesions both in-vivo and in-vitro .

A) Primary Objective

Assessment of:

• Dimensions of the WSLs through digital photography.

• The color of WSLs through spectrophotometer. B) Secondary Objectives

Assessment of:

• Degree of remineralization using Polarized Light Microscope.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Ain Shams University

Criteria

Inclusion criteria

• Patients aged from 8 to 12 years old

• Patients who are medically free from any diseases that would cause enamel defects.

• Patients should have WSLs in labial surface of upper or lower permanent anterior teeth with a score of 1 & 2 according to the ICDAS that don't require operative intervention.

Exclusion criteria

• Patients receiving the following medications will be excluded from the study:

tetracyclines, any other medication known to stain teeth, any medication causing dry mouth and/or xerostomia.

• Uncooperative patients

• Mouth breathers