To evaluate the efficacy and safety of 12-week goal-directed therapy in the treatment of
refractory inflammatory patients, and to initially explore treatment options. Patients with
potential risk factors for recurrence after surgery for Crohn's disease and a serum 25(OH)D
concentration <75 nmol/L were prescribed oral liquid vitamin D supplementation over 12 weeks
using a specific protocol with dose adjusted 4-weekly to aim for a target level of 100-125
nmol/L.
Phase:
Early Phase 1
Details
Lead Sponsor:
Nanjing University School of Medicine
Collaborator:
Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University