the Effect of Misoprostol on Intra-operative Blood Loss During Myomectomy Operation

• Status: Unknown status
• Trial end date: 2018-07-30
• Target enrollment: 0
• Participant gender: Female

Summary

assess the effect of using misoprostol in abdominal myomectomy operations on blood loss, duration of the operation and possible operative complications. Research question Does pre-operative misoprostol affect on intra-operative blood loss during and after myomectomy operation ?. Research hypothesis Pre-operative misoprostol may reduce intra-operative blood loss during and after myomectomy operation .

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: ahmed nagy shaker ramadan
• Treatments: Misoprostol

Criteria

Inclusion Criteria:

• Premenopausal patients aged between 35 to 50 years old.

• Five or less symptomatic uterine myomas .

• Maximum diameter of the largest myoma is 6 cm .

• All myomas are subserous or intramural.

• Uterine size less than 24 weeks pregnancy

Exclusion Criteria:

• History of previous surgery.

• Allergy to Misoprostol.

• Hypertension.

• Cardiac and Pulmonary diseases.

• Patients who have bleeding disorders.

• Anemia (Hb < 10g %).

• Chronic endocrine or metabolic diseases such as Diabetes.

• Obesity (body mass index > 30 kg/m2).

• Cases that will require intraoperative conversion of myomectomy to hysterectomy.