"The Role of the Liver for Interorgan Metabolic Crosstalk in Type 2 Diabetes"
Status:
Unknown status
Trial end date:
2021-02-20
Target enrollment:
Participant gender:
Summary
WP 1: Working hypothesis: The gluconeogenic flux rates from pyruvate (lactate, alanine) and
glycerol are higher in patients with T2D compared to the healthy control group.
WP2: Working Hypothesis: The gluconeogenic flux rates of lactate and glycerol are reduced in
patients with T2D by acute inhibition of the redox shuttle.
Phase:
N/A
Details
Lead Sponsor:
German Diabetes Center
Collaborator:
Prof. Dr. Gerald Shulman, Yale University, New Haven, Conneticut, USA