"The Efficacy of Exparel Versus a Multidrug Cocktail in Soft Tissue Tumors"

• Status: Recruiting
• Trial end date: 2023-07-07
• Target enrollment: 0
• Participant gender: All

Summary

The objective of this proposed project is to determine which local anesthetic is more efficacious for use in soft tissue tumors: Exparel (liposomal bupivacaine) or a cocktail of Ropivicaine, Epinepherine, Ketolorac and Clonidine. This study will examine patients' post-operative pain levels as well as their narcotic consumption after removal of a soft tissue tumor while hospitalized and then twice daily through postoperative day 14.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Morristown Medical Center
• Treatments: Clonidine; Epinephrine

Criteria

Inclusion Criteria:

• All primary soft tissue tumors

• Any adult patient (over 18 years old) with a soft tissue tumor confirmed with advanced imaging.

Two different study groups will be examined:

• Those patients undergoing resection of their soft tissue tumor intraoperatively injected with Exparel

• Those patients undergoing resection of their soft tissue tumor intraoperatively injected with the cocktail.

• Those two groups will be further stratified by anatomic location; Upper vs lower extremity, size; tumors ≥ 10cm, tumors ≥ 5cm, tumors < 5cm, and depth; superficial vs deep.

Exclusion Criteria:

• Pediatric Patients

• Patients without soft tissue tumors

• Tylenol or oxycodone allergy