"The Effect Of Subcutaneous Epinephrine Dosage On Blood Loss In Surgical Incision"

• Status: Not yet recruiting
• Trial end date: 2023-07-30
• Target enrollment: 0
• Participant gender: All

Summary

Several studies have attempted to calculate the ideal epinephrine concentration for vasoconstriction, however there has been little consensus. These experiments were carried out on animals, and the degree of vasoconstriction was measured using a variety of methods. Animal studies aren't always reliable since animal capillary density differs from human capillary density. Furthermore, because the density of capillaries in the head and neck is 30 to 40% higher than in other parts of the body, previous studies may not adequately reflect the ideal epinephrine concentration for this highly vascular location. As a result of this study, clinicians will be able to determine the appropriate dose of epinephrine to control intraoperative bleeding. This study aims to determine the effect of different doses of epinephrine on volume of bleeding in surgical incisions in participants undergoing supraclavicular flap surgery.

• Phase: Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Dow University of Health Sciences
• Treatments: Epinephrine

Criteria

Inclusion Criteria:

• Age≥ 18 years

• Patients who are undergoing supraclavicular flap surgery

• Patients wishing to be a part of study.

• Either gender

Exclusion Criteria:

• • Participants with cardio vascular diseases.

• Participants with collagen vascular diseases

• Participant who are on non-steroidal anti-inflammatory drugs, anticoagulants, or aspirin. .