"Red Morphine Drops" for Symptomatic Treatment of Dyspnoea in Lung Cancer

• Status: Completed
• Trial end date: 2011-02-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to test whether "red morphine drops" applied in the mouth are superior to an equivalent amount of morphine applied as subcutaneous injection for the relief of breathlessness in terminal patients suffering from primary lung cancer or lung metastases.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Sankt Lukas Hospice
• Treatments: Morphine

Criteria

Inclusion Criteria:

• Primary lung cancer or lung metastases and

• Moderate to severe dyspnea at rest (VAS equal to or more than 30)

Exclusion Criteria:

• Causal treatment of dyspnea possible and indicated

• Not receiving opioids on a regular basis

• Methadone treatment

• Intolerance to morphine

• Without understanding of patient information

• Depressed consciousness

• Oxygen treatment, if changed with-in 20 min before start

• Short-acting opioids with-in 4 h before start

• Inhalation therapy for bronchodilation with-in 20 min before start