"Acetic Acid Chromoendoscopy in Barrett's Esophagus Surveillance

• Status: Terminated
• Trial end date: 2018-07-30
• Target enrollment: 0
• Participant gender: All

Summary

Neoplasia in Barrett's esophagus could be missed during routine random biopsies. We propose a study using chromoendoscopy with Acetic Acid to increase the yield of biopsies in detecting neoplasia.

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: DHR Health Institute for Research and Development; Doctors Hospital at Renaissance
• Treatments: Acetic Acid; Retinol acetate

Criteria

Inclusion Criteria:

• Patients 18 years and older

• Previous diagnosis of Barrett's esophagus, confirmed by pathology.

Exclusion Criteria:

• Patients diagnosed with any level of dysplasia on previous esophageal biopsies.

• Patients who had esophageal therapy with Halo radiofrequency ablation in the past, or esophagectomy.

• History of allergy to Acetic Acid

• History of esophageal dysplasia or cancer

• Esophageal ulcerations

• Esophageal Candida

• Esophageal Varices

• Patients with active esophagitis

• Patients who cannot provide a valid consent

• Patients who are currently pregnant