Overview

n-Acetylcysteine and Cocaine

Status:
Completed

Trial end date:
2016-04-01

Target enrollment:

Participant gender:

Summary

This study will determine the initial efficacy, safety and tolerability of n-acetylcysteine as a pharmacotherapy for cocaine dependence. A rigorous, inpatient human laboratory study will be conducted in which the subjective, physiological and reinforcing effects of cocaine are evaluated during maintenance on placebo and n-acetylcysteine.

Phase:

Early Phase 1

Details

Lead Sponsor:

University of Kentucky

Collaborator:

National Institute on Drug Abuse (NIDA)

Treatments:

Acetylcysteine
Cocaine
N-monoacetylcystine