hCAP18 Levels and Vitamin D Deficiency in Chronic Kidney Disease
Status:
Withdrawn
Trial end date:
2014-12-01
Target enrollment:
Participant gender:
Summary
The human immune system produces a protein called hCAP18 (also known as LL-37 or
cathelicidin). This protein is believed to help the body to fight infections. Studies suggest
that vitamin D may important in the production of hCAP18. This study is designed to test the
ability of two different forms of vitamin D to affect levels of hCAP18. Vitamin D and hCAP18
levels will be measured during an initial visit. Individuals who are vitamin D deficient will
be randomly assigned to receive one of two forms of vitamin D for two weeks. After this,
follow-up levels will be measured.
Phase:
N/A
Details
Lead Sponsor:
Massachusetts General Hospital
Collaborators:
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) National Kidney Foundation