fMRI Study of Treatment Changes in Major Depression
Status:
Completed
Trial end date:
2014-01-01
Target enrollment:
Participant gender:
Summary
The overall purposes of this research are to determine if Cognitive Behavioral Therapy (CBT)
has the same healing effect on the brain for people with depression as traditional
antidepressants do, and in comparison to healthy controls with no history of depression, to
find out more about the causes of depression including differences in the extent of problems
caused by depression. We hypothesize that CBT will have the same healing effect on the brain
as antidepressants; that differences in brain activations created by the various tasks and
genetic differences will help us understand differences in the type and severity of symptoms
among the depressed subjects.