Overview

ctDNA Guiding Treatment After Almonertinib Induction Therapy for EGFRm+ NSCLC in the MDT Diagnostic Model

Status:
Not yet recruiting
Trial end date:
2024-08-15
Target enrollment:
Participant gender:
Summary
This is a multi-center, open phase II clinical study, in patients with unresectable stage III non-small cell lung cancer,to evaluate the effectiveness and safety of Almonertinib induction therapy, and ,to evaluate the effectiveness and safety of different treatment decisions guided by ctDNA dynamic monitoring after local treatments (surgical or radical radiotherapy) evaluated by MDT. The study includes a screening period (not more than 28 days after the subject signs informed consent to before the first medication), treatment period (including induction\MDT+topical therapy\adjuvant or consolidation therapy) and follow-up period (including safety and survival) .
Phase:
Phase 2
Details
Lead Sponsor:
Guangdong Association of Clinical Trials
Collaborator:
Jiangsu Hansoh Pharmaceutical Co., Ltd.