cAMP Signaling and Muscle Adaptations

• Status: Unknown status
• Trial end date: 2017-10-01
• Target enrollment: 0
• Participant gender: Male

Summary

The role of cAMP signaling mediated by beta2-adrenergic stimulation with agonists has been well-studied in skeletal muscles of animals. Studies in humans are scant and the scope of the present study is thus to investigate the role of cAMP signaling by beta2-adrenergic stimulation for muscle adaptations in humans.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of Copenhagen
• Treatments: Clenbuterol; Terbutaline

Criteria

Inclusion Criteria:

• healthy young men

• 18-35 years of age

• Informed consent

• Active 2-5 hours of training pr. week

• Maximal oxygen uptake (ml/min/kg) of 40-60

• Lean body mass of 55-65 kg / Lean mass index 14-22 kg/m2

Exclusion Criteria:

• Smoker

• Allergy towards study drugs

• Chronic disease