Zonisamide in the Treatment of Essential Tremor

• Status: Terminated
• Trial end date: 2012-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine if Zonisamide is effective in reducing tremors in patients with Essential Tremor.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Loma Linda University
• Treatments: Zonisamide

Criteria

Inclusion Criteria:

1. Diagnosis of Essential Tremor based on the Tremor Investigational Group criteria for definite or probable Essential Tremor.

2. Age: 18 years or over.

3. Willingness and ability to comply with the study requirements and give informed consent.

Exclusion Criteria:

1. Known history of psychiatric disorder, major depression, dementia, aplastic anemia, or Stevens-Johnson syndrome.

2. Known alcohol or substance abuse in previous 12 months.

3. Positive pregnancy test.

4. Unwillingness to use adequate contraceptive methods if of childbearing potential.

5. Known allergy to sulfonamides.

6. Laboratory abnormalities prior to onset of trial.