Zoledronic Acid Compared to Percutaneous Treatment in Osteoid Osteoma
Status:
Recruiting
Trial end date:
2023-05-24
Target enrollment:
Participant gender:
Summary
Osteoid osteoma (OO) is a benign osteogenic tumor occurring in children and young adults,
responsible for intense bone pain, which has a tendency to spontaneously heal with
mineralization of the nidus, but extremely slowly. This healing may be accelerated in
patients taking NSAIDs regularly during a few years. The long delay for healing and intense
pain, explain why patients are quickly directed to surgeons or specialized radiology
departments for tumor ablation. But percutaneous treatment or surgical excision destruction
can expose the patient to a substantial risk in terms of neurologic or joint damages,
depending on the location. Bisphosphonates treatment may be an effective alternative to
percutaneous treatment by accelerating the natural history of OO.