Overview

Zoledronate for Osteopenia in Pediatric Crohn's

Status:
Completed
Trial end date:
2008-11-01
Target enrollment:
Participant gender:
Summary
Background: - Up to 30% of children and adolescents with Crohn's disease have decreased bone strength, or decrease bone density, called osteopenia. - Bisphosphonates are a group of drugs that have been well studied and found to be effective in the treatment of osteopenia in menopausal women. - Zoledronate is a very potent third generation bisphosphonate, that is safe and easy to administer, and has been found effective in the treatment of menopausal women with osteopenia. Hypothesis: The investigators hypothesize that zoledronate can improve bone density in children and adolescents with Crohn's disease with osteopenia.
Phase:
Phase 3
Details
Lead Sponsor:
McGill University Health Center
McGill University Health Centre/Research Institute of the McGill University Health Centre
Collaborator:
Crohn's and Colitis Foundation
Treatments:
Diphosphonates
Zoledronic Acid