Zinc Supplementation on Very Low Birth Weight Infant
Status:
Unknown status
Trial end date:
2020-07-31
Target enrollment:
Participant gender:
Summary
Premature birth is a major cause of neonatal death in addition to neonatal asphyxia and
infections.
Early in life, premature babies must get aggressive nutrition so that there is no
extrauterine growth restriction (EUGR) in the Intrauterine Growth Restriction (IUGR) group
compared to the non-IUGR group.
Other factors that also play a role are long episodes of fasting, the fulfillment of
nutrition (macro and micronutrients) from the start, time to start breastfeeding (ASI),
duration of parenteral total administration, the incidence of respiratory distress syndrome
and incidence of necrotizing enterocolitis.
Zinc is one of the micronutrients which is very risky for deficiency in premature babies.
Babies with zinc deficiency experience growth disorders as much as 67%. In India, infants who
received zinc supplementation increased after being given 10 days of zinc supplementation and
lower mortality rates in the group with supplementation. Very low birth weight babies and
bronchopulmonary dysplasia who received zinc supplementation during the week showed good
clinical progress and the growth rate also increased.
The investigators believe this study has the potential for decreasing infant mortality from
its current level and can be a growth indicator for preterm babies.