Zinc Homeostasis and Kinetics in Children With Cystic Fibrosis (CF)
Status:
Completed
Trial end date:
2007-09-01
Target enrollment:
Participant gender:
Summary
Zinc deficiency has occasionally been reported in CF, but the need for additional zinc is
unclear. We will examine the effect of additional zinc supplements on zinc absorption, zinc
excretion, zinc balance and zinc kinetics in children with CF. Twelve children with CF will
receive additional zinc, and twelve will not. We will also compare the children with CF to 12
healthy children without CF. We hypothesize that children with CF will have poor zinc
absorption and high zinc excretion, leading to poor zinc balance and abnormal zinc kinetics.
We hypothesize that those children with CF who are given zinc supplements will have higher
zinc balance and more normal zinc kinetics than those without supplementation, and that zinc
balance and zinc kinetics will be similar to healthy children.
Phase:
N/A
Details
Lead Sponsor:
Cystic Fibrosis Foundation Cystic Fibrosis Foundation Therapeutics