Overview

Zidovudine, Interferon Alfa-2b, PEG-Interferon Alfa-2b in Patients With HTLV-I Associated Adult T-Cell Leukemia/Lymphoma

Status:
Terminated
Trial end date:
2011-11-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Human T-cell lymphotropic virus type 1 (HTLV-1) can cause cancer. Zidovudine is an antiviral drug that acts against the human T-cell lymphotropic virus type 1. Giving zidovudine, interferon alfa-2b, and PEG-interferon alfa-2b together may stimulate the immune system and slow down or keep the cancer cell from growing. PURPOSE: This clinical trial is studying how well giving zidovudine together with interferon alfa-2b and PEG-interferon alfa-2b works in treating patients with human T-cell lymphotropic virus type 1-associated adult T-cell leukemia/lymphoma.
Phase:
Phase 4
Details
Lead Sponsor:
University of Miami
Collaborator:
National Cancer Institute (NCI)
Treatments:
Interferon alpha-2
Interferon-alpha
Interferons
Peginterferon alfa-2b
Valproic Acid
Zidovudine