Yale Steroid Enhanced Versus Exparel Nerveblock TKA Part 2
Status:
Recruiting
Trial end date:
2026-03-01
Target enrollment:
Participant gender:
Summary
The objective of this study is to investigate the efficacy of Dexamethasone sodium phosphate
plus Methylprednisolone acetate in combination with plain bupivacaine ((B-DEX-MPA) compared
with Liposomal Bupivacaine in combination with plain bupivacaine (B-LB) on post-surgical pain
control among patients undergoing bilateral total knee arthroplasty (TKA) to asses if
perineural B-DEX-MPA will result in superior analgesia efficacy as compared to B-LB.
This study will also assess if perineural B-DEX-MPA results in improved quality of
postoperative recovery as compared to B-LB.
Phase:
Phase 2
Details
Lead Sponsor:
Yale University
Collaborator:
Department of Anesthesiology Faculty Development Fund