The purpose of this study is to determine whether a diet intervention (the Fasting Mimicking
diet) will help induce clinical and biochemical response to tofacitinib therapy in patients
with ulcerative colitis. Study period will be 8 weeks during induction of tofacitinib. The
primary aims of this study are to determine clinical response and improvement in fecal
calprotectin and C-reactive protein levels. Secondary outcomes will include assessment of
changes in the stool microbiome.