World Health Organization (WHO) COVID-19 Solidarity Trial for COVID-19 Treatments
Status:
Not yet recruiting
Trial end date:
2021-12-31
Target enrollment:
Participant gender:
Summary
In early 2020 there were no approved anti-viral treatments for COVID19 Infection. The
SOLIDARITY trial is a multicentre adaptive international randomised trial sponsored by Word
Health Organization to determine the efficacy of Remdesivir (daily infusion for 10 days), or
Acalabrutinib (orally twice daily for 10 days), or Interferon β1a(daily injection for 6 days)
compared with local standard of care in patients admitted to hospital for COVID19 infection
on all-cause mortality, stratified by severity of disease at the time of randomisation. The
major secondary outcomes are duration of hospital stay and time to first receiving
ventilation (or intensive care).