Whole Brain Radiotherapy With or Without Temozolomide at Daily Fixed-dose for Brain Metastases Treatment
Status:
Completed
Trial end date:
2009-10-01
Target enrollment:
Participant gender:
Summary
RATIONALE
- Fractionated radiotherapy uses high-energy photons to kill, or damage tumor cells. High
daily dose temozolomide combined with fractionated radiotherapy may make tumor cells
more sensible to treatment.
PURPOSE
- This randomized phase II trial, assess in patients with brain metastases from solid
tumors, whether the whole brain radiotherapy (WBRT) plus temozolomide is able to improve
the results obtained with WBRT.