Whole Blood Bactericidal Activity Against Mycobacterium Tuberculosis of Pyrazinamide Plus Allopurinol in Healthy Volunteers
Status:
Completed
Trial end date:
2016-04-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to evaluate the bactericidal activity against Mycobacterium
tuberculosis of pyrazinamide in combination with allopurinol. Pharmacokinetics (PK) and whole
blood bactericidal activity (WBA) will be measured in healthy volunteers following
administration of pyrazinamide alone and in combination with allopurinol.