What is the Best Moment for Performing an HSG in Women With a Unfulfilled Childwish

• Status: Recruiting
• Trial end date: 2025-01-01
• Target enrollment: 0
• Participant gender: Female

Summary

The aim of this study is to determine whether direct tubal flushing with oil-based contrast at HSG incorporated in the fertility work-up results in 10% more ongoing pregnancies and a shorter time to pregnancy, which will therefore be effective and cost-effective compared to delayed tubal flushing 6 months after fertility work-up is completed in women at low risk for tubal pathology.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Amsterdam UMC, location VUmc
• Collaborator: ZonMw: The Netherlands Organisation for Health Research and Development
• Treatments: Ethiodized Oil

Criteria

Inclusion Criteria:

• Women between 18-39 years of age

• Spontaneous menstrual cycle

• Perceived low risk for tubal pathology

• Undergoing fertility work-up

Exclusion Criteria:

• Women with known endocrine disorders (e.g. the polycystic ovary syndrome, diabetes, hyperthyroidism and hyperprolactinemia. Except for well managed hypothyroidism with TSH between 0.3 and 2.5mIU/l)

• Ovulation disorders defined as less than eight menstrual cycles per year

• Iodine allergy

• Male subfertility defined as a post-wash total motile sperm count < 1 x10^6 spermatozoa/ml

• Not willing or able to sign the consent form