What Amount of Stress is Enough for a Successful Conception?

• Status: Unknown status
• Trial end date: 2020-10-01
• Target enrollment: 0
• Participant gender: Female

Summary

The aim of the study is to determine whether premedication with midazolam before oocyte aspiration in IVF procedures affects the amount of (oxidative) stress in women undergoing IVF and whether stress is also transmitted to the follicular fluid of aspirated follicles. The primary endpoint is the impact of stress during aspiration on the success of medically assisted fertilization (IVF / ICSI in the stimulated cycle).

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University Hospital "Sestre Milosrdnice"
• Treatments: Midazolam

Criteria

Inclusion Criteria:

• Informed consent, healthy women undergoing IVF procedures for the first time

Exclusion Criteria:

• Refusal to enroll, chronic endocrine and psychiatric illnesses that might affect baseline stress levels