What After the First Propess

• Status: Recruiting
• Trial end date: 2022-01-01
• Target enrollment: 0
• Participant gender: Female

Summary

The aim of this study is to compare three different regimens for continuation of induction of labor after no spontaneous or artificial rupture of membranes could be achieved after first 24 hours post-insertion of Dinoprostone

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: South Warwickshire NHS Foundation Trust
• Collaborators: Medicem International; Walsall Healthcare NHS Trust
• Treatments: Dinoprostone

Criteria

Inclusion Criteria:

• Women booked for induction of labor at 37 to 42 weeks gestation

• Viable singleton pregnancy.

• Cephalic presentation.

• Intact membranes.

• No previous Caesarean section.

• No antenatal fetal concerns (Fetal growth restriction (FGR), small for gestational age (SGA), impaired Doppler, oligohydramnios, non-reassuring/abnormal CTG).

Exclusion Criteria:

• Pregnancy less than completed 37 weeks or more than 42 weeks.

• Multiple pregnancy.

• Intrauterine fetal death.

• Non-cephalic presentation.

• Pre-labor rupture of membranes

• Previous one or more Caesarean sections.

• Antenatal concerns regarding fetal well-being (FGR, SGA, impaired Doppler, oligohydramnios, non-reassuring/abnormal CTG).

• Non-reassuring or abnormal CTG on admission to labor ward