In current Dermatology practice, options for moderate acne vulgaris remain limited. The
mainstay of treatment for moderate acne remains long courses of oral antibiotics despite
emerging antibiotic resistance. The efficacy of daily to twice daily dosed isotretinoin, an
oral vitamin A derivative, for treatment of severe acne has been well established. The
purpose of this study is to determine if once weekly dosed isotretinoin is effective for the
treatment of patients with moderate acne. Additionally, the study aims to evaluate patient
satisfaction and identify any adverse effects on this alternative dosing regimen.