Weekly Cisplatin/Irinotecan and Radiotherapy in Patients With Locally Advanced Esophageal Cancer: Phase II Trial
Status:
Completed
Trial end date:
2004-12-01
Target enrollment:
Participant gender:
Summary
The standard non surgical therapy of locally advanced esophageal cancer is based on a
definitive concurrent chemoradiotherapy regimen with fluorouracil and cisplatin. One of the
alternative regimen which is being studied is the combination of a weekly cisplatin and
irinotecan schedule with radiotherapy. This multicentric phase II clinical trial primarily
aimed to evaluate the clinical complete response rate and secondary objectives were toxicity
profile and survival.