Vorinostat and Gemcitabine in Treating Patients With Metastatic or Unresectable Solid Tumors
Status:
Completed
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
This phase I trial is studying the side effects and best dose of vorinostat and gemcitabine
in treating patients with metastatic or unresectable solid tumors. Drugs used in
chemotherapy, such as vorinostat and gemcitabine, work in different ways to stop the growth
of tumor cells, either by killing the cells or by stopping them from dividing. Vorinostat may
also stop the growth of tumor cells by blocking some of the enzymes needed for cell growth
and by blocking blood flow to the tumor. Giving more than one drug (combination chemotherapy)
may kill more tumor cells.