Vorinostat and Capecitabine in Treating Patients With Metastatic or Unresectable Solid Tumors
Status:
Completed
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy, such as vorinostat and capecitabine, work in different
ways to stop the growth of tumor cells, either by killing the cells or by stopping them from
dividing. Vorinostat may also stop the growth of tumor cells by blocking some of the enzymes
needed for cell growth. Giving more than one drug (combination chemotherapy) may kill more
tumor cells.
PURPOSE: This phase I trial is studying the side effects and best dose of vorinostat and
capecitabine in treating patients with unresectable or metastatic solid tumors.