Vorinostat and Alvocidib in Treating Patients With Advanced Solid Tumors
Status:
Completed
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
This phase I trial is studying the side effects and best dose of vorinostat when given
together with alvocidib in treating patients with advanced solid tumors. Drugs used in
chemotherapy, such as vorinostat and alvocidib, work in different ways to stop the growth of
tumor cells, either by killing the cells or by stopping them from dividing. Vorinostat may
also stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.
Giving vorinostat together with alvocidib may kill more tumor cells.