Overview

Vonoprazan-containing Triple Therapy Versus Empiric Bismuth Quadruple Therapy for First-line Helicobacter Pylori Treatment: a Randomized Clinical Trial

Status:
Not yet recruiting

Trial end date:
2026-02-06

Target enrollment:

Participant gender:

Summary

Vonoprazan Amoxicillin and metronidazole based triple therapy had achieved a high cure rate in the rescue treatment of helicobacter pylori infection. This study aims to evaluate the efficacy and safety of the Vonoprazan, amoxicillin and metronidazole based triple therapy and the empiric bismuth quadruple therapy in the naive patients with Helicobacter pylori infection.

Phase:

Phase 4

Details

Lead Sponsor:

Shanghai East Hospital

Treatments:

Amoxicillin
Bismuth
Esomeprazole
Metronidazole
Potassium Citrate