Overview

Volume vs Concentration: Quadratus Lumborum Blocks With High Volume/Low Concentration or Low Volume/ High Concentration in Nephrectomies

Status:
Withdrawn

Trial end date:
2021-08-01

Target enrollment:
0

Participant gender:
All

Summary

The quadratus lumborum has since 2016 become standard of care for abdominal and retroperitoneal surgeries at UPMC-Shadyside Hospital, replacing paravertebral blocks, and as part of a broader multimodal analgesia institutional Enhanced Recovery After surgery protocol. Since the first description of this technique, several approaches to and anatomic targets within the quadratus lumborum plane have been described although their mechanism of action, spread, and relative clinical effectiveness remain areas of some debate. What is proposed here is to investigate the relative clinical effectiveness of the relationship high volume/low concentration of local anesthetic or low volume/ high concentration of local anesthetic.

Phase:

Phase 4

Accepts Healthy Volunteers?

Details

Lead Sponsor:

Bruce Ben-David

Treatments:

Ropivacaine

Criteria

Inclusion Criteria:

1. Patients 18-90 years old

2. Patients undergoing nephrectomy

3. Body Mass Index 19-36

4. Male and Female

5. All races

6. American Society of Anesthesiologist scale I, II, III

Exclusion Criteria:

1. Patient refusal

2. Pregnancy

3. Non-English speaking or inability to participate in the study

4. Patients with coagulopathy or With International Normalized Ratio >1,5 the day of the
surgery.

5. Chronic steroid use

6. Chronic pain

7. Chronic opiate use