Volume Kinetics for 20% Albumin in Different Clinical Situations
Status:
Unknown status
Trial end date:
2019-04-01
Target enrollment:
Participant gender:
Summary
The study aims to determine the degree of plasma volume expansion and the half-life of the
plasma volume expansion when 3 mL/kg of hyperoncotic (20%) albumin if infused over 30 minutes
in conscious healthy volunteers, in patients undergoing surgery under general anesthesia, and
on the day after major surgery when the patient is in a post surgical inflammatory state. The
study also examines the increase in the plasma colloid osmotic pressure as a result of this
infusion and its possible influence on markers of kidney damage.
Phase:
Phase 4
Details
Lead Sponsor:
Sodertalje Hospital
Collaborators:
Karolinska University Hospital University Hospital, Linkoeping