Vitamins and Minerals for Children With Downs Syndrome
Status:
Completed
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
The trial aimed to examine the effects of supplementation with antioxidants and folinic acid
on the health, growth and psychomotor development of children with Down syndrome. 156
children with Trisomy 21, less than 7 months of age were recruited and randomised into four
groups to receive antioxidants, folinic acid, a combination of antioxidants and folinic acid
or a placebo. Blinded outcome assessment was carried out 18 months later.Blood and urine
samples were also taken around 12 months of age to examine metabolic effects of
supplementation.