The purpose of this pilot trial is to test the safety and efficacy of administering one dose
of vitamin E, via a tube into the stomach, to extremely preterm infants (less than 27 weeks
gestation and less than 1000 grams birth weight). This pilot will examine whether a single
dose of vitamin E will be absorbed into the infants' bloodstreams with resulting serum
α-tocopherol level in the target range of 1-3 mg/dl.
Phase:
Phase 1
Details
Lead Sponsor:
NICHD Neonatal Research Network
Collaborators:
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) National Center for Research Resources (NCRR)
Treatments:
alpha-Tocopherol Tocopherols Tocotrienols Vitamin E Vitamins