Patients with multiple sclerosis (MS) have an increased risk of developing a major
depression. The investigators observed a protective effect of high vitamin D levels on the
risk of depression in MS. This might be driven by the effect of vitamin D on the stress-axis.
Therefore, the main goal of the present study is to assess whether high dose vitamin D
supplementation results in a suppression of the stress-axis, as measured by decreased levels
of cortisol.
Phase:
Phase 2
Details
Lead Sponsor:
Academic MS Center Limburg
Treatments:
Cholecalciferol Ergocalciferols Vitamin D Vitamins