Vitamin D in Patients With Stage I-III Colon Cancer or Resectable Colon Cancer Liver Metastases
Status:
Recruiting
Trial end date:
2022-05-31
Target enrollment:
Participant gender:
Summary
This study seeks to learn more about the vitamin D receptor and its relationship to colon
cancer. The Vitamin D receptor is found in colon cancer cells. When Vitamin D binds to the
receptor in the cancer cells, it may stop cancer cells from growing abnormally and may cause
cancer cell death. Vitamin D has been used in other research studies and information from
those other research studies suggests that Vitamin D may help in the treatment of colon
cancer.
Participants will receive either high-dose vitamin D or standard-dose vitamin D. The study
drug will be given 14-28 days prior to your surgery. The number of days will depend on when
the surgery is scheduled.
Phase:
Early Phase 1
Details
Lead Sponsor:
Dana-Farber Cancer Institute
Collaborators:
National Cancer Institute (NCI) Pharmavite Pharmavite LLC
Treatments:
Cholecalciferol Ergocalciferols Vitamin D Vitamins