Vitamin D and Physical Activity for Prevention of Sarcopenia in Osteoporosis
Status:
Completed
Trial end date:
2011-09-01
Target enrollment:
Participant gender:
Summary
In the present study the aim was to determine the prevalence of sarcopenia and to evaluate
the effectiveness of an exercise program and vitamin D supplementation in enhancing muscle
mass and strength in community-dwelling older adults with osteopenia /osteoporosis.
One hundred and forty-five individuals aged 65 years and above with documented
osteopenia/osteoporosis were scanned for sarcopenia. The participants were randomly assigned
to one of four groups: Group 1-PA and vitamin D (n= 38), Group 2-PA(n=36), Group 3-vitamin D
(n= 36) or Group 4-healthy lifestyle(n =35) for 16 weeks. The PA group received a 60-minute
3-day/week exercise programme, the vitamin D group received oral cholecalciferol 2000 IU/day
and the control group was provided with health education using videotaped presentations,
physician talks on topics concerning bone and muscle health. Body composition was measured
DEXA. Vitamin D levels were measured and PA was measured using the Baecke Physical Activity
Questionnaire. Physical performance was assessed using upper limb grip strength, walking
speed and knee extension strength. All data was collected at baseline and at 4 months.
Phase:
N/A
Details
Lead Sponsor:
Faculty of Medicine, University of Alexandria University of Alexandria
Treatments:
Cholecalciferol Ergocalciferols Vitamin D Vitamins