Vitamin D and Omega-3 Adiposity Trial (VITAL Adiposity)
Status:
Active, not recruiting
Trial end date:
2022-07-01
Target enrollment:
Participant gender:
Summary
The VITamin D and OmegA-3 TriaL (VITAL; NCT 01169259) is a randomized clinical trial in
20,000 U.S. men and women investigating whether taking daily dietary supplements of vitamin
D3 (2000 IU) or omega-3 fatty acids (1 gram of omega-3 fatty acids) reduces the risk of
developing cancer, heart disease, and stroke in people who do not have a prior history of
these illnesses. This ancillary study (VITAL Adiposity) is being conducted among participants
in VITAL and will examine the effect of vitamin D or fish oil on changes in body composition
and adiposity (baseline compared to 2 year, as measured by anthropometric indices, total and
regional body fat and adipokines) and assess whether changes in cardiovascular risk factors
(lipids, glucose tolerance, blood pressure) are mediated by these parameters. How achieved
25(OH)D levels are affected by body composition and body mass will also be assessed.
Phase:
N/A
Details
Lead Sponsor:
Brigham and Women's Hospital
Collaborator:
American Heart Association
Treatments:
Cholecalciferol Ergocalciferols Vitamin D Vitamins