Vitamin D and Chronic Renal Insufficiency

• Status: Completed
• Trial end date: 2011-01-01
• Target enrollment: 0
• Participant gender: All

Summary

Purpose of this study is to investigate the effect of treatment with vitamin D3 (cholecalciferol) compared with placebo in a trial including chronic kidney disease patients with vitamin D deficiency.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Odense University Hospital
• Treatments: Cholecalciferol; Ergocalciferols; Vitamin D; Vitamins

Criteria

Inclusion Criteria:

• Chronic kidney disease (CKD 3-5 amd renal transplanted patients)

• Age > 18 years

• Vitamin D insufficiency or deficiency (25-OHD < 50 nmol/l, 3 months before project start)

Exclusion Criteria:

• Treatment with vitamin D2/D3 (dose more than 10000 IU within the last 3 months)

• Hypercalcaemia (ca++ > 1,35 mmol/l more than 4 weeks despite missing intake of calcium containing preparations and activated vitamin D)

• Uncontrolled hyperphosphataemia (s-phosphate > 2,2 mmol/l)

• Sarcoidosis

• Malignant disease

• Psychotic disorders

• Pregnancy and lactation women

• Allergy to soya and peanut