Vitamin D Supplementation for Acute Bronchiolitis

• Status: Completed
• Trial end date: 2018-12-01
• Target enrollment: 0
• Participant gender: All

Summary

This study was conducted to evaluate the effect of oral vitamin D supplementation on the clinical course of acute bronchiolitis, and to investigate whether vitamin D deficiency among infants who required hospital-based care for bronchiolitis is associated with the severity of the acute episode.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Mansoura University
• Treatments: Cholecalciferol; Ergocalciferols; Vitamin D; Vitamins

Criteria

Inclusion Criteria:

• Infants aged 1-24 months of age, diagnosed clinically as acute bronchiolitis and presented with any of the following:

1. Persistent resting oxygen saturation below 92% in room air.

2. Marked tachypnea.

3. Intercostal retractions indicating respiratory distress.

4. Inability to maintain oral hydration.

5. Parent unable to care for child at home.

Exclusion Criteria:

1. Infants with history of prematurity (< 37 weeks), chronic cardiopulmonary disease, immunodeficiency, neuromuscular disease, and any other chronic medical condition.

2. Patients receiving any micronutrient supplementation or therapies containing vitamin D for 4 weeks prior to the study period.

3. Infants with previous episodes of wheezing or a physician's diagnosis of asthma.

4. Patients with acute bronchiolitis having very severe clinical score.