Overview

Vitamin D Supplementation Requirement in Obese Subjects

Status:
Completed
Trial end date:
2011-08-01
Target enrollment:
0
Participant gender:
All
Summary
Vitamin D deficiency is common in obese patients. Most of vitamin D supplementation studies were done with non-obese subjects. This study looks at vitamin D supplementation requirements in obese patients as compared to non-obese subjects. This study also looks at changes in vitamin D level in obese patients undergoing medical weight loss. It is thought that obese patients have vitamin D deficiency through storage of vitamin D in the fat compartment not readily available for blood measurement. The investigators' hypothesis is that with medical weight loss vitamin D levels will increase in obese subjects.
Phase:
N/A
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Winthrop University Hospital
Treatments:
Cholecalciferol
Ergocalciferols
Vitamin D
Vitamins
Criteria
Inclusion Criteria:

- Healthy men or women between the ages of 18 and 70 years old who are enrolled in our
Weight Management Program with baseline BMI > 30 Kg/m2.

Exclusion Criteria:

- Pregnancy,

- Serum 25(OH)D level greater than 80 nmol/L,

- Hypercalcemia (serum calcium level greater than the upper limit of normal),

- Recent surgery or illness,

- Those with chronic use of medications that influence calcium/vitamin D metabolism such
as anti-convulsants, lithium and steroids. Thiazide diuretics for hypertension will be
acceptable.

- Subjects with sarcoidosis will be excluded.

- Those who do not qualify to participate in the Weight Management Program will be
excluded. They include subjects with active substance abuse and unstable cardiac
disease.