Vitamin C and Atrial Fibrillation After Cardiac Surgery

• Status: Withdrawn
• Trial end date: 2015-08-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine if vitamin C decreases the chance of developing atrial fibrillation, a type of arrhythmia or irregular heartbeat, following cardiac surgery. This irregular heartbeat is a common occurrence following cardiac surgery, and occurs in about one third of patients. It poses extra risks to people who develop it. Our hypothesis is that Vitamin C will decrease the incidence of postoperative atrial fibrillation.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Regional Hospital of Scranton
• Treatments: Ascorbic Acid; Vitamins

Criteria

Inclusion Criteria:

• Adults 50 years of age or older

• Undergoing elective or urgent coronary artery bypass graft surgery, valve surgery, or a combination of the two

Exclusion Criteria:

• Prior cardiac surgery

• History of atrial fibrillation

• Permanent or temporary pace maker

• Currently taking digoxin or Vaughan Williams Class I or III antiarrhythmic medications

• Known hyperoxaluria

• History of renal calculi

• History of allergic or hypersensitivity reaction to ascorbic acid products

• Currently taking 1 g or more of ascorbic acid supplementation daily