The VItamin C, Thiamine And Steroids in Sepsis (VICTAS) Study is a double-blind,
placebo-controlled, adaptive randomized clinical trial designed to investigate the efficacy
of the combined use of vitamin C, thiamine and corticosteroids versus indistinguishable
placebos for patients with sepsis. The objective of this study is to demonstrate the efficacy
of combination therapy using vitamin C, thiamine and corticosteroids in reducing mortality
and improving organ function in critically ill patients with sepsis.