Vitamin B Complex and Diabetic Nephropathy in Type 1 Diabetes
Status:
Completed
Trial end date:
2018-04-02
Target enrollment:
Participant gender:
Summary
Homocysteine levels have been found elevated in T1DM patients with Diabetic nephropathy (DN)
due to several causes, including dietary deficiencies. Hyperhomocysteinemia induces renal
injury and is associated with increasing urinary albumin excretion(UAE). Therefore, the
investigators performed a randomized-controlled trial of oral supplementation with vitamin B
complex as an adjuvant therapy for nephropathy in pediatric patients with T1DM and assessed
its relation to homocysteine levels, glycemic control, microalbuminuria and cystatin C as a
marker of nephropathy.