This study was a randomized, community-based trial testing whether dosing newborn infants in
the first few days after delivery with a large dose of vitamin A could reduce early infant
morbidity, mortality and improve growth. Pregnant women in 2 districts of Tamil Nadu State in
southern India were identified and recruited for participation. When the child was born,
study staff were notified and traveled to the house to collect information and provide the
vitamin A or placebo dose. Children were visited every two weeks until they were 6 months of
age to collect information about vital status and morbidity. All children were discharged
from the study at 6 months after growth was assessed and they received a 100,000 IU dose of
vitamin A.
Phase:
Phase 3
Details
Lead Sponsor:
Johns Hopkins Bloomberg School of Public Health
Collaborator:
Aravind Centre for Women and Children, Madurai, Tamil Nadu, India