Overview

Vitamin A Supplementation With Routine Childhood Vaccines and Mortality and Morbidity

Status:
Unknown status

Trial end date:
2014-12-01

Target enrollment:
0

Participant gender:
All

Summary

Vitamin A supplementation (VAS) is important for the immune system and may interact with different childhood vaccinations. We have hypothesized that the improved survival after VAS may depend on vitamin A amplifying the non-specific immune modulation induced by vaccinations. In the present study we used information collected in connection with a national vitamin A campaign in Guinea-Bissau during which different doses of VAS was provided together with missing doses of DTP, OPV, and measles vaccines. We aimed to study the potential interactions between VAS and vaccine type.

Phase:

Phase 4

Accepts Healthy Volunteers?

Details

Lead Sponsor:

Bandim Health Project

Treatments:

Retinol palmitate
Vaccines
Vitamin A
Vitamins

Criteria

Inclusion Criteria:Between 6 months and 5 years and thus eligible for vitamin A and missing
vaccines during national immunisation days -

Exclusion Criteria: Overt signs of vitamin A deficiency

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